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Description Field Ind Field Data
Leader LDR nam1i 00
Control # 1 201002ISP004
Control # Id 3 MOCL
Date 5 20230109131003.0
Linking 6 m eo d
Phy Descr 7 cr cn |||m|||a
Fixed Data 8 100317s2010 caua foab 000 0 eng d
ISBN 20    $a9781615040407 (electronic bk.)
ISBN 20    $z9781615040391 (pbk.)
Std Rec No. 24 $a10.4199/C00007ED1V01Y201002ISP004$2doi
Local Ctrl # 35    $a(CaBNVSL)gtp00539042
Local Ctrl # 35    $a(OCoLC)698257125
Obsolete 39    $a332243$cTLC
Cat. Source 40    $aCaBNVSL$cCaBNVSL$dCaBNVSL
LC Call 50  4 $aRC694.3$b.R856 2010
NLM Call # 60  4 $aQZ 170$bR843p 2010
Dewey Class 82 04 $a616.135$222
ME:Pers Name 100 $aRumbaut, Rolando E.
Title 245 10 $aPlatelet-vessel wall interactions in hemostasis and thrombosis$h[electronic resource] /$cRolando E. Rumbaut and Perumal Thiagarajan.
Imprint 260    $aSan Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :$bMorgan & Claypool,$cc2010.
Phys Descrpt 300    $a1 electronic text (viii, 67 p. : ill.) :$bdigital file.
Series:Diff 490 $aSynthesis lectures on integrated systems physiology, from molecules to function,$x1947-9468 ;$v# 4
Note:General 500    $aPart of: Colloquium digital library of life sciences.
Note:General 500    $aSeries from website.
Note:Bibliog 504    $aIncludes bibliographical references (p. 45-67).
Note:Content 505 $a1. Introduction -- 2. General characteristics of platelets -- Overview -- Platelet granules -- Alpha granules -- Dense granules -- Lysosomes -- Platelet adhesion molecules -- P-selectin -- Glycoprotein Ib/IX/V (GPIb/IX/V) -- Glycoprotein IIb/IIIa (GP IIb/IIIa) -- Collagen receptors -- G-protein-coupled receptors -- Thrombin -- Adenosine diphosphate (ADP) and adenosine triphosphate (ATP) -- Prostanoids --
Note:Content 505 $a3. Platelet adhesion to vascular walls -- Adhesion to subendothelium following vascular injury -- Von Willebrand factor (vWF) -- Collagen -- Other subendothelial components -- Endogenous mechanisms preventing platelet adhesion to endothelium -- Nitric oxide -- Prostacyclin -- Ecto-adenosine diphosphatase (ADPase) -- Endothelial surface layer -- Mechanisms of platelet adhesion to endothelium -- Endothelial P-selectin-dependent mechanisms -- Endothelial vWF-dependent mechanisms -- Other mechanisms --
Note:Content 505 $a4. Platelet aggregation -- Mechanisms of platelet aggregation -- Monitoring of platelet aggregation -- Ex vivo monitoring: platelet aggregometry -- In vivo monitoring of platelet aggregation --
Note:Content 505 $a5. Platelet recruitment and blood coagulation -- Role of platelets -- Role of platelet-leukocyte interactions --
Note:Content 505 $a6. Arterial, venous, and microvascular hemostasis/thrombosis -- Venous thrombosis -- Endothelial injury -- Hypercoagulability -- Stasis -- Coexistence of Virchow's triad components: cancer and thrombosis -- Arterial thrombosis -- Microvascular thrombosis --
Note:Content 505 $a7. Summary -- Bibliography.
Abstract 520 $aPlatelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.
Note:Addl Fm 530    $aAlso available in print.
Tag 588 588    $aTitle from PDF t.p. (viewed on March 17, 2010).
Subj:Topical 650  0 $aThrombosis.
Subj:Topical 650  0 $aHemostasis.
Subj:Topical 650  0 $aBlood platelets.
AE:Pers Name 700 $aThiagarajan, Perumal.
Host Item 773 $tBuhl Colloquium eBooks
SE:Ufm Title 830  0 $aColloquium digital library of life sciences.
SE:Ufm Title 830  0 $aColloquium series on integrated systems physiology.
Elec Loc'n 856 40 $uhttp://dx.doi.org/10.4199/C00007ED1V01Y201002ISP004$yClick for access to full text electronic version of this title.