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Description Field Ind Field Data
Leader LDR nam1i 00
Control # 1 201111ISP030
Control # Id 3 MOCL
Date 5 20221118114334.0
Linking 6 m eo d
Phy Descr 7 cr cn |||m|||a
Fixed Data 8 120112s2012 caua foab 000 0 eng d
ISBN 20    $a9781615043583 (electronic bk.)
ISBN 20    $z9781615043576 (pbk.)
Std Rec No. 24 $a10.4199/C00048ED1V01Y201111ISP030$2doi
Local Ctrl # 35    $a(CaBNVSL)swl00400393
Local Ctrl # 35    $a(OCoLC)768892079
Obsolete 39    $a332282$cTLC
Cat. Source 40    $aCaBNVSL$cCaBNVSL$dCaBNVSL
LC Call 50  4 $aQP145$b.G785 2012
NLM Call # 60  4 $aWI 102$bG785n 2012
Dewey Class 82 04 $a612.3$223
ME:Pers Name 100 $aGrundy, David.
Title 245 10 $aNeural control of gastrointestinal function$h[electronic resource] /$cDavid Grundy, Simon Brookes.
Imprint 260    $aSan Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :$bMorgan & Claypool,$cc2012.
Phys Descrpt 300    $a1 electronic text (ix, 123 p.) :$bill., digital file.
Series:Diff 490 $aColloquium series on integrated systems physiology, from molecule to function to disease,$x2154-5626 ;$v# 30
Note:General 500    $aPart of: Colloquium digital library of life sciences.
Note:General 500    $aSeries from website.
Note:Bibliog 504    $aIncludes bibliographical references (p. 91-123).
Note:Content 505 $a1. Neural control of gastrointestinal function -- 1.1 Introduction -- 1.2 Structure of the gut wall -- 1.3 Region-specific functions --
Note:Content 505 $a2. Cells and tissues -- 2.1 Cells in the mucosa: enterocytes -- 2.2 Cells in the mucosa: goblet cells -- 2.3 Cells in the mucosa: entero-endocrine cells -- 2.4 Cells in the mucosa: paneth cells -- 2.5 Cells in the lamina propria: mast cells -- 2.6 Cells in the lamina propria: other immune cells -- 2.7 Smooth muscle cells of the muscularis externa -- 2.8 Interstitial cells of cajal (ICCS) -- 2.9 Fibroblast-like cells of the muscularis externa -- 2.10 Enteric neurons and glial cells --
Note:Content 505 $a3. Enteric nervous system -- 3.1 Introduction -- 3.2 The ganglionated plexuses -- 3.3 Enteric glial cells -- 3.4 Enteric neural circuits -- 3.5 Classes of enteric neurons -- 3.5.1 Smooth muscle motor neurons -- 3.5.2 Enteric sensory neurons -- 3.5.3 Enteric interneurons -- 3.6 Electrophysiology of motor neurons and interneurons -- 3.7 Other classes of enteric neurons -- 3.7.1 Viscerofugal neurons -- 3.7.2 Secretomotor and vasomotor neurons -- 3.8 Differences between species and regions of gut -- 3.9 Physiology of the enteric nervous system -- 3.10 Fast excitatory neurotransmission -- 3.11 Slow excitatory neurotransmission -- 3.12 Inhibitory neurotransmission in enteric ganglia -- 3.13 Presynaptic inhibition and facilitation -- 3.14 Neurotransmission to other non-neuronal cells --
Note:Content 505 $a4. From gut to CNS: extrinsic sensory innervation -- 4.1 Introduction -- 4.2 Pathways to the CNS -- 4.3 Classes of visceral afferents -- 4.4 Axon reflexes -- 4.5 Mechanosensitivity -- 4.6 Serosal and mesenteric afferents -- 4.7 Muscle afferents -- 4.8 Mucosal afferents -- 4.9 Muscular-mucosal afferents -- 4.10 Transduction mechanisms -- 4.11 Chemosensitivity -- 4.12 Chemotransduction -- 4.13 Central pathways of vagal afferent information -- 4.14 Central pathways of spinal afferent information -- 4.15 Visceral representation in the brain -- 4.16 Central sensitisation --
Note:Content 505 $a5. Sympathetic innervation of the gut -- 5.1 Pathways -- 5.2 Synaptic drive -- 5.3 Sympathetic circuitry -- 5.4 Sympathetic influences on motility -- 5.5 Sympathetic influences on secretion -- 5.6 Sympathetic influences on blood flow --
Note:Content 505 $a6. Parasympathetic innervation of the gut -- 6.1 Introduction -- 6.2 Pathways -- 6.2.1 Vagus -- 6.3 Brainstem reflexes -- 6.4 Sacral parasympathetic pathways --
Note:Content 505 $a7. Integration of function -- 7.1 Motility reflexes -- 7.2 Swallowing -- 7.3 Gastric motility -- 7.4 Gastric acid secretion -- 7.5 Small intestinal motility -- 7.6 "Fed behaviour" of the small intestine -- 7.7 Polarised reflex pathways -- 7.8 Peristalsis -- 7.9 Migrating motor complexes (MMCs) -- 7.10 Colonic motility -- 7.11 Distension of distal colon in vitro -- 7.12 Colonic MMCs -- 7.13 Defaecation -- 7.14 Secretory and vasomotor reflexes -- 7.15 Integration of gastrointestinal function with food intake regulation -- 7.16 Nausea and vomiting -- 7.17 Stress and the gut -- 7.18 Neuro-immune interactions in the gut --
Note:Content 505 $aReferences.
Abstract 520 $aThe gastrointestinal tract is a long, muscular tube responsible for the digestion of food, assimilation of nutrients and elimination of waste. This is achieved by secretion of digestive enzymes and absorption from the intestinal lumen, with different regions playing specific roles in the processing of specific nutrients. These regions come into play sequentially as ingested material is moved along the length of the GI tract by contractions of the muscle layers. In some regions like the oesophagus transit it rapid and measured in seconds while in others like the colon transit is measured in hours and even days, commensurate with the relative slow fermentation that takes place in the large bowel. An hierarchy of controls, neural and endocrine, serve to regulate the various cellular targets that exist in the gut wall. These include muscle cells for contraction and epithelial cells for secretion and absorption. However, there are complex interactions between these digestive mechanisms and other mechanisms that regulate blood flow, immune function, endocrine secretion and food intake. These ensure a fine balance between the ostensibly conflicting tasks of digestion and absorption and protection from potentially harmful ingested materials. They match assimilation of nutrients with hunger and satiety and they ensure that regions of the GI tract that are meters apart work together in a coordinated fashion to match these diverse functions to the digestive needs of the individual. This ebook will provide an overview of the neural mechanisms that control gastrointestinal function.
Note:Addl Fm 530    $aAlso available in print.
Tag 588 588    $aTitle from PDF t.p. (viewed on January 12, 2012).
Subj:Topical 650  0 $aGastrointestinal system$xInnervation.
AE:Pers Name 700 $aBrookes, Simon.
Host Item 773 $tBuhl Colloquium eBooks
SE:Ufm Title 830  0 $aColloquium digital library of life sciences.
SE:Ufm Title 830  0 $aColloquium series on integrated systems physiology.
Elec Loc'n 856 40 $uhttp://dx.doi.org/10.4199/C00048ED1V01Y201111ISP030$yClick for access to full text electronic version of this title.